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CT-388 could potentially fit into the treatment paradigm if the following criteria based on clinical studies are met: Efficacy: CT-388 should demonstrate significant weight loss that is sustained over a longer-term period, as obesity requires chronic management

It is discrete, hyperpigmented macules or patches on genitalia and histopathologically, the number of melanocytes is normal, but there is increased basal layer hyperpigmentation with lack of melanocytic hyperplasia (5)

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