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4.2 Mechanisms of enzymatic degradation and the regulatory networks of the glycocalyx In general, there is greater catabolism of proteins, lipids, and carbohydrates in sepsis (59), but recent studies have shown that there is also greater polysaccharide synthesis in endothelial cells in the presence of sepsis

However, many people suffer from Vitamin B12 deficiency due to various reasons, including poor dietary intake, absorption issues, or certain medical conditions

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FUT2 (the "secretor" gene, variant rs602662) is one of the strongest common genetic determinants of circulating B12 levels