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Groups More Likely to Experience Nausea Clinical data indicate that nausea is more common in: First-time PT-141 users Patients receiving higher initial doses Premenopausal women treated for hypoactive sexual desire disorder (HSDD) Those with prior medication sensitivity or a history of motion sickness Additional caution is warranted in patients with cardiovascular disease due to the medications potential effects on blood pressure

(PubMed) Wijdicks EF

Pathophysiology: Tendinopathy, Tendinosis, and Fasciopathy Tendinopathy comprises pain and dysfunction from mechanical overload, altered collagen cross-linking, and neovascularization