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A Monday morning shot means you are hitting peak suppression by Tuesday or Wednesday, carrying strong effects through the typical workweek when structured eating is easiest

This altered gastric emptying can modify the entire digestive process, affecting how quickly food is broken down and absorbed throughout the gastrointestinal tract

"Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes (SUSTAIN 2)"

A 2024 study published found that 98% of reported cases of GLP-1-related pancreatitis were classified as serious, highlighting the need for increased medical caution