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Cognitive impairments are also widespread, ranging from subtle executive function deficits to severe disorientation, with minimal hepatic encephalopathy present in up to 80% of cirrhosis patients

Clinical Evidence: What the OASIS 4 Trial Tells Us About the Wegovy Pill The FDA approval of oral semaglutide 25 mg for chronic weight management was based primarily on the results of the OASIS 4 Phase 3 clinical trial a 64-week, randomized, double-blind, placebo-controlled study that enrolled 307 adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

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