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Maneechotesuwan K , Kasetsinsombat K , Wamanuttajinda V , Wongkajornsilp A , Barnes PJ

Observational study - a human research study in which no experimental intervention or treatment is applied, and participants are simply observed over time Oxidative stress - a situation in which the production of reactive oxygen species exceeds the ability of an organism to eliminate or neutralize them Placebo - a chemically inactive substance Plaque - a deposit of fat, cholesterol, immune cells, fibrin (a clotting protein), and other substances that forms inside arterial walls Randomized controlled trial - a human research study in which participants are assigned by chance alone to receive either an experimental agent (the treatment group) or a placebo (the control group) Reactive oxygen species (ROS) - highly unstable oxygen-containing compounds that react easily with nearby cellular structures, potentially causing damage Test tube - a research experiment performed in a test tube, culture dish, or other artificial environment outside of a living organism

This imbalance can lead to cellular damage and has been associated with various pregnancy complications, including preeclampsia and gestational diabetes

Both refer to the same naturally occurring copper peptide