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This research validates the physical reality of "brain fog" and cognitive dysfunction, showing it is not a psychological symptom but a direct result of localized antioxidant depletion and cellular energy failure

Proc Natl Acad Sci U S A 101:1505215057 Hicks LM, Cahoon RE, Bonner ER, Rivard RS, Sheffield J, Jez JM (2007) Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thaliana