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(146) observed significant blood-to-brain influx for non-acylated GLP-1 mimetics like exendin-4 and lixisenatide, whereas acylated GLP-1 analogues such as liraglutide and semaglutide showed minimal blood-brain barrier penetration in mice

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PMCID: PMC7084196

The World Anti-Doping Agency is collecting evidence of athletes using the GLP-1 weight loss drugs for a competitive advantage and could ban them before the 2028 Olympics in Los Angeles