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Mechanisms of GST-mediated insecticide resistance have been depicted as occurring either directly via the GST conjugation reaction (phase I) or via metabolism of secondary products by other detoxifying enzymes, such as P450 (phase II) [122]
Parameters such as pH, temperature, light, ions, enzymes, and magnetic fields have the potential to induce the release of the payload [86]
For this reason, researchers sometimes refer to glutathione as the detox molecule. 12 Lu SC
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