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Plaque angiogenesis assay in vivo For the in vivo plaque angiogenesis assay, the conditioned media from cancer cells were mixed with Matrigel and then subcutaneously injected into 8-week-old NOD.Cg-Prkdcscid/JNarl mice were provided by the National Laboratory Animal Center in Taiwan

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It is currently believed that GLP-1R mainly signals through the Gs/cAMP pathway, although evidence also suggests that GLP-1R interacts with Gq and other G proteins

10.1002/ptr.7311 310 ZhangQ.HuangY.LiX.LiuH.HeB.WangB.et al (2019)