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Focused update on intracranial atherosclerosis: Introduction, highlights, and knowledge gaps

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The toxic effects of AFB1 arise through its enzymatic activation by cytochromes P450 to form highly reactive AFB1-8,9-epoxides

Healthy storage of adipose tissue delays the progressive insulin resistance associated with obesity 74 , providing a plausible hypothesis that if GIPR agonism in adipose tissue can promote lipid storage in the correct location, this could result in positive effects on insulin sensitivity