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(2005) used an adenovirus-delivered small interfering RNA (siRNA) method to observe the knockdown of c-Met on tumorigenic growth of HCC in in vitro and in vivo trials In the in vitro trial, compared with adenovirus alcohol dehydrogenase (AdH1)-null or mock-infected cells, proliferation of MHCC97-L cells, which had high c-Met expression, were inhibited by adenovirus AdH1-siRNA, and c-Met expression also decreased

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Therefore, sll0067 along with the two Chi-class cyanobacterial GSTs, TeGST, and SeGST, are the first few examples of bacterial enzymes with high specific activity than the mammalian enzymes

Gynecological Endocrinology , 36(4), 362-367