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References Global Burden of Disease Network (2021) Global burden of disease study 2021 (GBD 2021) Results

Table 3: Percent (%) of Type 1 Diabetes Patients Experiencing at Least One Episode of Severe Hypoglycemia or Hypoglycemia on TRESIBA in Open Label Adult and Pediatric Clinical Trials Table 4: Percent (%) of Patients with Type 2 Diabetes Experiencing at Least One Episode of Severe Hypoglycemia or Hypoglycemia on TRESIBA in Open Label Adult Clinical Trials Hypersensitivity Reactions Severe, life threatening, generalized allergy, including anaphylaxis, generalized skin reactions, angioedema, bronchospasm, hypotension, and shock have occurred with insulin, including TRESIBA and may be life threatening

For an injectable product like semaglutide, sterility testing is particularly critical

What pushes one month higher than another Several inputs move the number