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Biotin deficiency can cause dry skin, brittle nails and hair, as well as hair loss

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Nitrosative stress is also present, as illustrated by markers of nitrosative stress such as increased NOS and NO (182, 297), peroxynitrite (182, 297), elevated NF- production (182), and nitrate after exercise (182, 297)

The participants applied 2% oxidized glutathione (GSSG) lotion to one side of their face and a placebo lotion to the other side, twice daily for 10-weeks