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Due to the current lower consumption of fruits and vegetables, it may be difficult to acquire sufficient exogenous antioxidants, so ensuring this intake is essential to the redox balance in cellular homeostasis [42]

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Wang found that in RSL3-induced ferroptosis, both the protein expression and acetylation level of ALOX12 were significantly increased, thereby aggravating intracellular phospholipid peroxidation [35]

Where trials discuss the resolution of side effects, one trial reported that around half of affected participants taking dutasteride reported spontaneous resolution of symptoms while continuing treatment