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doi: 10.1111/bcpt.12307 51 CozzolinoAFeolaTSimonelliIPulianiGPozzaCGianettaEet al

Since 90% of the bodys serotonin originates in the gut, modulating enteric serotonin production could influence central serotonergic tone through vagal afferents that relay gut signals to brain serotonin-producing raphe nuclei