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Unlike angiotensin IV, which cannot effectively penetrate brain tissue, Dihexa possesses the unique ability to cross the blood-brain barrier when administered orally, making it a viable candidate for therapeutic applications in neurodegenerative conditions

For imaging, the worms were mounted on a 2% agarose pad and images were captured using a Leica compound microscope (Leica DM5000B)

Research limitations The most significant safety consideration involves research limitations

By optimizing skeletal muscle metabolism and counteracting metabolic decline, MOTS-c addresses the fundamental cellular machinery responsible for energy balance