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Name: acetyl l carnitine examine L-Carnitine benefits, dosage, and side effects Ketogenic diet mediates intestinal tumorigenesis
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3.2.2 Mitochondrial pathway Mitochondria serve as a central regulator of intrinsic apoptosis

11 GSH depletion and the subsequent low stores of protein thiol result in both calcium release from intracellular stores and inhibition of calcium extrusion, producing a marked increase in cytosolic calcium concentration, which triggers cytotoxicity