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Another recently discovered therapeutic strategy in ASD is targeting a small GTPase, RhoA, that is involved in cellular cytoskeleton structure and motility [136], and has found to be upregulated in some ASD models while being downregulated in others [34, 137,138,139]

Holotranscobalamin (holoTC, or active b12) Another useful test is the holoTC test (or active-B12 test), which measures the portion of B12 bound to transcobalamin

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