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Given that dietary intake is the primary source of Mn, the intestines serve as a major site of Mn regulation (Kippler and Oskarsson, 2024)

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Additionally, disruption of the balance between mitochondrial fission and fusion, along with impaired fatty acid metabolism, is closely linked to intracellular calcium overload in various cell types [3335]

Sometimes the medication may not work for you, or you may not be able to tolerate the full dose due to side effects in which case your practitioner will provide additional options or change the protocol to better suit your individual needs