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J.ShaivitzA.et al

Leukemia 22(9):1728-1736, 2008

For example, low estrogen in the early follicular stage, may negatively affect RE-induced increases in estrogen levels (Hansen et al., 2012), while, in the luteal phase where circulating progesterone is relatively high, may also counteract the sensitizing effects of estrogen on muscle impairing any benefit of acute RE-induced during these phases (Hansen, 2018)

and is needed to determine whether muscle tissue utilizes carbohydrates or fat for energy