g) optionally, purifying semapeptide, wherein semapeptide amino acid sequence is Glu-Gly-Thr- Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-A present invention involves fermentation process for increase in accumulation of expressed semapeptide by inducing transformant prokaryotic cells in culture medium with chemical agent
Cancer Res 56 : 40134020 Dunn SE, Ehrlich M, Sharp NJ, Reiss K, Solomon G, Hawkins R, Baserga R, Barrett JC (1998) A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer
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