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Nature 583 , 590595 (2020)

Post-Surgical and Convalescence Support: During recovery from surgery or illness, the bodys demand for nutrients often increases

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In human growth-hormone-deficiency trials using recombinant native IGF-1 (mecasermin, brand name Increlex), the approved dose range is 0.04-0.12 mg/kg twice daily by subcutaneous injection, titrated to IGF-1 levels in the age- and sex-normalised reference range [15]