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Abnormal small intestinal permeability to sugars in patients with Crohn's disease of the terminal ileum and colon

In addition, hBMSCs treatment was found to be safe, with no tumor formation observed in mice after injection and no detectable integration of human DNA into the offspring genome [124]

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Moreover, lipid peroxidation-driven plasma membrane rupture will accelerate KRAS-mediated pancreatic tumorigenesis by promoting DAMPs release, resulting in the activation of inflammatory pathways and polarization of macrophages for tumor growth [234]