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For individuals with less fat, pinching the skin can help

The recent SELECT trial, a four-year study, has been pivotal in establishing this connection

The studies also met a key secondary endpoint, endoscopic improvement

Furthermore, this trend toward increased alpha diversity in the obese groups placed on an LD that had consequently experienced weight loss aligns with clinical observations, where low gene richness has been associated with increased adiposity, insulin resistance, and dyslipidemia 70 while increased gene richness has been observed following dietary intervention in obese and overweight individuals 71