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As regards the developmental efforts to increase muscle quality, bezafibrate, which has been used to treat liver cirrhosis and targets PPARs, is the subject of a phase II clinical trial on T2DM, and chiglitazar sodium, a PPAR pan-agonist, recently approved in China for the treatment of T2DM (Table 1) [171]

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.,RadovanovicJ,BanjacK,ObradovicMIsenovicERAntioxidant enzymes and vascular diseases.2021;2(6):544555