When interpreted in conjunction with the transcriptomic enrichment analysis, these findings suggest that EGCG-Zn may exert its protective effects through coordinated modulation of inflammation- and junction-related signaling pathways
Song L, Cao L, Liu R, Ma H, Li Y, Shang Q,
Therefore, increased ROS/RNS levels induced by several clinical conditions may play a deleterious effect on different biomolecules (e.g., lipids, proteins and nucleic acids), organelles and antioxidant defenses, leading to exacerbate nitro-oxidative stress, mitochondrial dysfunction, glial activation and inflammatory response
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