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Safety, tolerability, pharmacokinetics, and pharmacodynamics of the first-in-class GLP-1 and amylin receptor agonist, amycretin: a first-in-human, phase 1, double-blind, randomised, placebo-controlled trial

[1] [3] The pancreas plays a dual role in metabolism: its endocrine cells produce hormones like insulin and glucagon, while exocrine cells secrete digestive enzymes

10.3390/molecules28176403 Molecules

One study from Liu-Ambrose et al observed significant reductions in global brain volume following 1 year of high-intensity progressive RT (2 sets of 6-8 repetitions at 70%85% of 1RM, either once or twice weekly) in older women free from MCI (Liu-Ambrose et al., 2010)