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One author (DAA) has received consulting fees from VAL Health, Thrive Global, and SelectDr, and payment from Deloitte, outside the submitted work

Treatment usually begins with a lower dose (0.25 mg weekly for four weeks) to minimise gastrointestinal side effects rather than for glycaemic control, with gradual increases to 0.5 mg and potentially 1 mg or 2 mg based on individual response and tolerability