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21 Therefore, anti-oxidation and promoting epidermal repair are the main two most effective ways to treat skin photoaging, which currently include topical retinoids, antioxidants, and laser therapies, but these methods often yield temporary results and side effects such as redness triggered by retinoids and damage caused by the laser, prompting exploration into innovative therapeutic strategies

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26 Therefore, we suggest that hypertensive individuals with the 718C variant of the GPX4 gene are susceptible to CS because of the increased concentration or activity of the enzyme promoting proinflammatory processes and increasing the brain injury