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Regul Pept (2004) 121(13):13743.10.1016/j.regpep.2004.04.014 50 LeeSJLeeJLiKKHollandDMaughanHGuttmanDSet alDisruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis

In addition, oral VK2735 demonstrated encouraging safety and tolerability following 28 days of once-daily dosing, and no serious adverse events (SAEs) have been reported to date

doi:10.1681/ASN.0000000000000344 104

2.5 Dry eye disease (DED) One of the main causes of eye care visits is dry eye disease (DED), a complex ailment of the ocular surface and tear film that causes pain, visual disturbances, tear film instability, and possible ocular surface damage [34,35,36]