glp 1 elevated liver enzymes Therapeutic Mechanisms and Clinical Effects of Glucagon-like Peptide Receptor Agonists in Nonalcoholic Fatty Disease Potential effects of GLP-1 and

Because GLP-2 acts through subepithelial myofibroblasts, which are the same cell population implicated in intestinal fibrogenesis, the risk-benefit profile of GLP-2 agonism may differ substantially between mucosal UC, inflammatory ileal CD, and stricturing or penetrating CD phenotypes, and this phenotypic stratification should be a required feature of future trial design

Succinic semialdehyde (4-oxobutanoate) acts as a suitable substrate analog` as this molecule only lacks the 3-hydroxy group of MSA (3-hydroxy-4-oxobutanoate) which could be added in silico

Atiq M, Holt AF, Safdar K, Weber F, Ravinuthala R, Jonas ME, Neff GW

Its because it helps the body absorb it better