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Patients self-injecting vitamin B12 without telling their GP, finds study A large proportion of patients with a vitamin B12 deficiency self-inject medication sourced online, citing difficulty with accessing treatment from GPs

no large-scale controlled trials Lack of FDA approval process No sponsor has pursued formal approval Quality concerns Peptide impurities and characterization challenges in unregulated manufacturing The economic reality: Unpatentable peptides cant justify the $50100M+ investment required for Phase 3 clinical trials, which is why BPC-157 has peer-reviewed preclinical data but no completed human trials

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