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Miguens-Gomez 2021): A fast, neural-based release within 10-15 minutes of eating A slower, nutrient-based release ~60 minutes after eating, especially when nutrients reach the lower GI tract, Eating too quickly may short-circuit the gut-brain connection
Trial SURMOUNT-OSA (NEJM 2024) Population 469 adults with moderate-to-severe OSA + obesity
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Nearly 4% of users who reported side effects mentioned menstrual changes, things like irregular cycles, heavy bleeding, or intermenstrual bleeding, and these symptoms arent prominently featured in the current prescribing information. When you consider that were looking at a mixed-gender sample on Reddit, and that Reddit skews male, the true rate among women taking these medications could potentially be higher, Sehgal said
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