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On the other hand, AMPK activates selective autophagy (such as mitophagy), thereby eliminating ROS and mitochondrial DNA (mtDNA) released from damaged mitochondria

The same study showed partial protection from cisplatin-induced toxic neuropathy a common chemotherapy side effect (Catania et al., 2003)

This review aims to explore the cellular processes underlying ferroptosis and the therapeutic implications for drug development in treating ocular diseases

The analysis could be affected by residual confounding from unsupervised lifestyle modifications, and importantly, the reasons for treatment discontinuation were not recorded