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Moreover, the KYN pathway, which is altered in both depression and CKD, has been implicated in gut permeability and immune dysregulation, further linking the gut-brain axis with kidney dysfunction (Kearns, 2024)

Foundayo (orforglipron) is an oral daily GLP-1 analog related to semaglutide (prices should be compared to that of compounded semaglutide) that is available for self-pay through LillyDirect at It can be taken with or without food

Other Ingredients: Acid-resistant capsule (hypromellose, gellan gum, and water), microcrystalline cellulose, stearic acid, magnesium stearate, and silica

Calms anxiety and promotes clarity: Provides nutrients that help reduce anxiety and enhance mental clarity, supporting better cognitive function