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Description

Launched by Eli Lilly in late 2023, Zepbound combines GLP-1 and GIP receptor agonism to deliver superior weight loss compared to single agonists

Refer to peer-reviewed scientific literature when making research decisions.

In a published Phase 2 trial (48 weeks), adults with obesity who took retatrutide lost, on average, more weight at higher doses, with the 12 mg group showing 24.2% average weight change at 48 weeks (compared with 2.1% in the placebo group)

Heart failure: promotes sodium and water excretion, reducing cardiac workload, and lowering risk of hospitalization and cardiovascular death