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The article says branded production is standardized at large scale with established stability data across temperature ranges and shelf-life conditions

Scientific American published a great article detailing how these drugs make this possible

Enterococcus faecalis ) possess an enzyme that decarboxylates levodopa in the intestine before it can be absorbed, effectively reducing the drugs availability [168, 169]

However, idiosyncratic reactions, such as mixed hepatocellular-cholestatic injury, have been documented, underscoring the necessity of monitoring both transaminases and cholestatic markers such as alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) (Sauder et al