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Acknowledgments We are thankful to all the members of the Department of Neuro-Oncology, Institute of Brain Science, Graduate School of Medical Sciences, Nagoya City University, for their feedback on the manuscript

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A Booming Anti-Obesity Drug Discovery Landscape at a Glance (With Challenges) In 1986, Danish scientist Jens Juul Holst discovered that the gut hormone GLP-1 stimulates insulin and suppresses appetite

While sermorelin's GI side effects are generally mild, combination therapy might increase symptom burden