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Allerdings knnen Situationen mit langanhaltender starker oxidativer Belastung wie Infektionen oder die chronische Belastung mit Umweltgiften die Glutathion-Konzentration in den Zellen erschpfen und immer weiter absenken 1

A number of potential H4R-bearing candidate cells in the colon may participate in this process, some of which are known direct sources of IL-6 in the colon (innate cells such as MCs, neutrophils, and macrophages) and others that may play an intermediate role, like natural killer T cells