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After 20 min at room temperature, chromatin configurations were analyzed using fluorescence microscopy (Eclipse 80i, Nikon Instruments Europe, Amsterdam, The Netherlands) at 40 magnification with an excitation (Ex) filter of 365/28 nm, a dichroic mirror (DM) of 405 nm and an emission (Em) filter of 445/50 nm

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Abstract Chronic kidney disease (CKD) is a progressive condition characterized by the gradual loss of kidney function, leading to the accumulation of uremic toxins in the bloodstream