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Milder Discomfort: Intramuscular injections are generally less invasive than intravenous infusions, and some individuals may find them more tolerable in terms of discomfort

Tirzepatide generally produces faster and greater weight loss, but it also costs more through MEDVi and may produce stronger initial side effects during the titration phase

Despite the large unmet demand for rapidly acting interventions, more research on the interaction between these facets of gut-based modulation is necessary to fully capitalize on the considerable potential of gut-based interventions in psychiatry, specifically for motivational dysfunctions