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GHK-Cu (glycyl-L-histidyl-L-lysine bound to copper(II)) has been used for decades in low-concentration topical cosmetics with a generally favorable tolerability record, but there is almost no published human adverse-event data especially for injectable or systemic research use
Nat Commun 7:11321 Lukey MJ, Cluntun AA, Katt WP et al (2019) Liver-type glutaminase GLS2 is a druggable metabolic node in luminal-subtype breast cancer
Stricker BH, Biriell C
Phase II then neutralises these through conjugation reactions including sulphation, glucuronidation, and glutathione conjugation which is why glutathione supplement support is so relevant to liver health
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