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Regulation of Postnatal Bone Lengthening Endocrine and Paracrine Factors The process of postnatal bone elongation is tightly controlled by 1) systemic endocrine molecules, such as hormones distributed through blood that act on target cells of the growth plate, and 2) locally produced paracrine/autocrine factors expressed in epiphyseal chondrocytes or surrounding perichondrium

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Estimating this visually introduces imprecision