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Additionally, elevated expression of toll-like receptors (TLRs) is observed in the brains of PD patients, where they co-localize with -syn in Lewy bodies and trigger inflammatory responses (56)

In addition to its role in energy metabolism with some antioxidant properties, L-acetyl-carnitine can cross the blood-brain barrier, where it modulates brain neurotransmitters, such as acetylcholine, serotonin and dopamine, and acts on neurotrophic factors by modifying the activity of the relevant genes

You're shifting cellular behavior toward more youthful patterns across multiple systems