Unlike peptides that target a single receptor or hormone, copper peptide influences gene expression, collagen production, inflammation, and antioxidant defense at the same time
While retinoids increase photosensitivity and require careful sun avoidance, GHK-Cu protects keratinocytes from lethal UV-B radiation and blocks UV-induced erythema without making skin more sensitive to sun exposure
In this review, we emphasize on (1) GSH depletion as a fundamental risk factor for diseases like chronic obstructive pulmonary disease and atherosclerosis (ischemic heart disease and stroke), (2) importance of oxidative stress and antioxidants in SARS-CoV-2 infection and COVID-19 disease, (3) significance of GSH to counteract persistent damaging inflammation, inflammaging and early (premature) inflammaging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses in younger individuals, and (4) new therapies that include antioxidant defenses restoration
doi:10.1097/CRD.0000000000000513 Kruse T, Hansen JL, Dahl K, et al