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43 Exenatide significantly decreased TNF-, MCP-1 and ROS secretion, which may be associated with the activation of adenylate-activated protease (AMPK) and inhibited the inflammatory process through interaction with NF-B, CCAAT/enhancer binding protein (C/EBP) and mitogen-activated protein kinase (MAPK) (p38, ERK and JNK)

GLP-1/GIP Dual Agonism GIP is an entero-pancreatic hormone secreted from K-cells of the duodenum/upper jejunum in response to ingestion of nutrients [24]

Armbrecht HJ, Hodam TL, Boltz MA (2003) Hormonal regulation of 25-hydroxyvitamin D 31a-hydroxylase and 24-hydroxylase gene transcription in opossum kidney cells

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