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Description

Benefits appear mediated through weight reduction rather than direct anti-inflammatory effects on joints

Nausea, vomiting, diarrhea, and stomach discomfort are the most common complaints

Alli (orlistat): An over-the-counter medication that is FDA-approved for weight loss in overweight adults, used in combination with a reduced-calorie, low-fat diet to help people lose weight

This weight loss is thought to be due to the increased glucose excretion in the urine, although the exact mechanism may vary