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(3) In naturally aged mice, FOXO4-DRI treatment reduced senescent cell burden, improved liver and kidney function, restored exercise tolerance (grip strength and running capacity), and improved coat appearanceall markers of healthier aging

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Ueda P, Wintzell V, Melbye M, Eliasson B, Svensson A-M, Franzn S, et al

Inclusion criteria encompassed all studies employing in vitro models (e.g., fibroblast proliferation, keratinocyte migration, collagen synthesis assays), in vivo studies using animal models for wound healing assessments, clinical trials evaluating the efficacy and safety of tripeptides in human subjects, and studies utilizing molecular, biochemical, or histological analyses to determine the mechanisms of tripeptides in wound recovery