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CD47 is an inhibitory receptor that is expressed on the surface of normal cells and tumour cells

Moreover, it has been found that the human multidrug resistance protein (MRP), a member of the superfamily of ATP-binding cassette membrane transporters, can lead to resistance to multiple classes of chemotherapeutic agents [70, 71]

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Figure 8 Many different genes responsible for growth factors, regulatory molecules of the cell cycle, cytokines, inflammatory cytokines and anti-inflammatory molecules can be expressed through oxidatived stress induced activation of several transcription factors